We are guided by a quality control policy. Super Fildena combines sildenafil citrate and dapoxetine, making it a dual-action medication for treating both erectile dysfunction (ED) and premature ejaculation (PE).
| Point | Explanation | Additional Tips |
|---|---|---|
| Take as directed | Follow prescribed dose and timing | Do not exceed recommended dose |
| Avoid alcohol | Can impair effectiveness and increase side effects | Limit or abstain before use |
| Report adverse effects | Seek medical attention if serious reactions occur | Especially priapism or severe dizziness |
| Ensure medical consultation | Before starting, especially if on other meds | For personalized advice |
Sildenafil citrate, a potent vasodilator, enhances blood flow to the penile to facilitate erections, while dapoxetine prolongs the time to ejaculation, improving control over climax.
The authors concluded that tadalafil can increase the mean IELT and can be used for treatment of PE in combination with paroxetine. Flushing episodes, as a side effect, were more obvious in group 2 (P = 0.000) [Citation18]. performed a meta-analysis involving 17 trials with 5,739 participants. Seven single medications (paroxetine, fluoxetine, dapoxetine, sertraline, sildenafil, tadalafil and placebo) and five combination therapies were included (tadalafil with sildenafil, tadalafil with fluoxetine, paroxetine with sildenafil, dapoxetine with mirodenafil, and sildenafil with fluoxetine). They concluded that the combination of phosphodiesterase-5 inhibitors and SSRIs were more effective than monotherapy [Citation19].
Elbakary and colleagues evaluated the effectiveness of sildenafil combined with dapoxetine for treating PE. Eighty patients with PE without erectile dysfunction were allocated into 2 groups. The 1st group (40 patients) were given on- demand dapoxetine 30 mg for three months, the 2nd group (40 patients) received an on-demand combination of dapoxetine 30 mg and sildenafil 50 mg for three months. The means of pretreatment and posttreatment IELT among groups were 51.72 ± 12.53 vs 322 ± 24.62 in group 1 and 56.6 ± 10.93 vs 352.5 ± 29.33 in group 2 (P < 0.001). They concluded that combination therapy was associated with better improvement than mono-therapy [Citation20]. This combination offers comprehensive relief for men experiencing both sexual performance issues simultaneously.
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Users often report improved sexual satisfaction and increased confidence.
Participants in group 1 were given tadalafil 5 mg and participants in group 2 were given a combination therapy of dapoxetine 30 mg with tadalafil 5 mg. The means of pretreatment IELT were 1.49 ± 0.51 and 1.47 ± 0.57 minutes in group 1 and 2 respectively. The means of post-treatment IELT were 7.35 ± 4.31 and 9.07 ± 4.2 minutes in groups 1 and 2, respectively, with statistically significant improvements in group 2 (P = 0.045) [Citation21]. Abu El-Hamd M and Abdelhamed A evaluated 150 patients with PE without erectile dysfunction. Five groups of participants, each with 30 patients, were randomly allocated.
For a six-week period, participants in each group received an on-demand placebo, paroxetine (30 mg), dapoxetine (30 mg), sildenafil (50 mg), and a combination of dapoxetine (30 mg) with sildenafil citrate (50 mg). Each participant was told to record his IELT results. The means of pretreatment IELT were 40.33 ± 8.6, 38.66 ± 9.9, 38.86 ± 10.35, 38.66 ± 9.9, and 38.33 ± 10.02 and the means of posttreatment IELT were 41.33 ± 8.3, 173.86 ± 19.8, 171.83 ± 20.7, 175.5 ± 22.4, 266 ± 36.6 in groups 1, 2, 3, 4, 5, respectively. The combination of dapoxetine and sildenafil had the greatest outcomes (p value < 0.001). Headache, nausea and flushing had been the most prevalent side impacts linked with the combination therapy [Citation22]. Like any medication, Super Fildena may cause side effects such as headaches, nausea, or dizziness, typically mild and temporary.
Consultation with a healthcare provider is recommended before starting this treatment.
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In this study, the mean IELT was lower sildenafil and dapoxetine than in other studies as most of our patients did not seek medical advice except if PE is severe and responsible for major negative personal and partnership consequences. In this study headache and flushing, as adverse effects of treatment, were more pronounced in group 3 with a statistically significant variation (P = 0.036, < 0.001). For clinical implications, we recommend to start with a single drug and shift to the combination therapy in patients who are not improved by monotherapy. This work had some limitations including short follow-up period, after therapy was stopped, individuals were not observed, and it was not placebo controlled. Both tadalafil and dapoxetine are effective in the treatment of PE as a single drug, but the combination of both gives more pronounced improvement, however with a slightly increased incidence of side effects.
The combination of both drugs in cases who are not satisfied with monotherapy can be considered. No potential conflict of interest was reported by the author(s). Efficacy and safety of dapoxetine/sildenafil combination tablets in the treatment of men with premature ejaculation and concomitant erectile dysfunction—DAP-SPEED study. An evidence-based unified definition of lifelong and acquired premature ejaculation: report of the second international society for sexual medicine ad hoc committee for the definition of premature ejaculation. Desk reference to the diagnostic criteria from DSM-5-TR. Dapoxetine is not intended for regular daily use – you should only take it before you anticipate having sex.
| Aspect | Details | Recommendations |
|---|---|---|
| Abuse potential | Moderate, especially for recreational purposes | Use only as prescribed |
| Dependence | Rare, but psychological reliance possible | Monitor usage, seek help if needed |
| Withdrawal symptoms | Not well-documented, but consult doctor if discontinuing | Gradual tapering may be advised |
Take them to your local pharmacy which will dispose of them for you.
Washington, DC: American Psychiatric Association Publishing,; 2022. p. 1. online resource. Shabsigh R, Rowland D.
The diagnostic and Statistical manual of mental disorders, fourth edition, text revision as an appropriate diagnostic for premature ejaculation. doi: 10.1111/j.1743-6109.2007.00557.x Premature ejaculation-emerging concepts and a Novel classification. The premature ejaculation prevalence and attitudes (PEPA) survey: prevalence, comorbidities and professional help-seeking. Help-seeking behaviour for sexual problems: the global study of dapoxetine 30mg tablet sexual attitudes and behaviors. Efficacy of PDE5Is and SSRIs in men with premature ejaculation: a new systematic review and five meta- analyses. If you have any problems with the way your liver works, or if you have any problems with the way your kidneys work.
Comparison between tadalafil plus paroxetine and paroxetine alone in the treatment of premature ejaculation. Dapoxetine for the treatment of premature ejaculation: a meta-analysis of randomized controlled trials with trial sequential analysis. A prospective randomized study comparing the efficacy and safety of sildenafil with dapoxetine in treatment of premature ejaculation. Which one is the best in premature ejaculation treatment? Comparison of the clinical efficacy and safety of the on-demand use of paroxetine, dapoxetine, sildenafil and combined dapoxetine with sildenafil in treatment of patients with premature ejaculation: a randomised placebo-controlled clinical trial.
Dr. Srishti Rastogi is a medical writer and healthcare professional dedicated to high-quality patient education and public health awareness. Leveraging her clinical background, she produces deeply researched, evidence-based content for digital health platforms and medical publications. Dr. Srishti’s unique dual perspective as a clinician and communicator allows her to craft content that builds trust and credibility with readers navigating sensitive health topics. The recommended starting dose is one 30 mg tablet, taken 1 to 3 hours before you anticipate having sex.Each film-coated tablet contains dapoxetine hydrochloride equivalent to 30 mg or 60 mg dapoxetine.
| Parameter | Value | Notes |
|---|---|---|
| Absorption Rate | Rapid | Peak plasma in 1-2 hours |
| Half-Life | 21 hours | Longer duration for sustained effect |
| Metabolism | Liver (CYP2D6 and CYP3A4) | Biotransformation process |
| Excretion | Urine | Main route of elimination |
The most common AE was nausea and occurred in %, % and % of subjects with placebo, dapoxetine 60 mg and dapoxetine mg respectively.
Guidelines on male sexual dysfunction: Erectile dysfunction and premature ejaculation. doi: 10.1016/j.eururo.2010.02.020 Emerging treatments for premature ejaculation: Focus on dapoxetine. Utility of selective serotonin reuptake inhibitors in premature ejaculation. Phosphodiesterase 5 inhibitors in rapid ejaculation: potential use and possible mechanisms of action. Is there a role for phosphodiesterase type-5 inhibitors in the treatment of premature ejaculation?
Development and evaluation of an abridged, 5-item version of the International Index of erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction. Short-term analysis of the effects of as needed use of sertraline at 5 pm for the treatment of premature ejaculation. doi: 10.1016/S0090-4295(99)00187-9 Gillman N, Gillman M. Premature ejaculation: Aetiology and treatment strategies. Comparison of dapoxetine/tadalafil and paroxetine/tadalafil combination therapies for the treatment of the premature ejaculation: a randomized clinical trial. This medication is used to treat male sexual dysfunction such as premature ejaculation.