Sildenafil treats erectile dysfunction or pulmonary hypertension (high blood pressure in the arteries that send blood to the lungs for oxygen).

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A typical starting dose of sildenafil is 50 milligrams, which you’d take 30 minutes to four hours before sexual activity. Your provider may adjust your dosage depending on your needs and how you respond to the medication. It’s also possible you may get a prescription in doses that are multiples of 20 milligrams, including 20 milligrams, 40 milligrams, 60 milligrams, and 80 milligrams. In these cases, your sildenafil tablets would actually be the generic form of Revatio®, a medication that has the ingredient sildenafil, like Viagra, but is FDA-approved for pulmonary arterial hypertension (although it can be prescribed off-label for ED). Be sure to talk through all options with your healthcare provider.

Usual Adult Dose for:

And, as is the case with taking any medication, following a professional’s medical advice is crucial. Unlike some other ED meds, you don’t take sildenafil every day. Sildenafil is an as-needed medication that should be taken at least about 30 minutes to an hour before sexual activity, and its effects should last up to four hours. You should never take more than one dose per day. You may be prescribed sildenafil or Viagra if you struggle with the following symptoms: Getting erections that aren't as firm as you'd like them to be Getting erections that aren't as firm as you'd like them to be Some medications can upset your stomach if you don’t take them with food. Dosage strengths and dosage schedules are very different for these two medical conditions.

Product Dosage Quantity + Bonus Price
Viagra Generic50mg20 Pills40.52€ 38.59€
Kamagra100mg120 + 6 Pills330.74€ 314.99€
Kamagra100mg60 + 4 Pills201.34€ 191.75€
Viagra Generic25mg20 Pills37.74€ 35.94€
Kamagra Soft Tabs100mg120 + 6 Pills311.78€ 296.93€
Kamagra Oral Jelly100mg21 Sachets95.92€ 91.35€
Kamagra Oral Jelly100mg10 Sachets54.55€ 51.95€
Kamagra Soft Tabs100mg60 + 4 Pills180.59€ 171.99€
Viagra Generic25mg10 Pills25.19€ 23.99€
Viagra Generic100mg30 + 4 Pills60.91€ 58.01€
Kamagra Polo100mg12 Pills60.21€ 57.34€
Viagra Generic200mg120 + 8 Pills204.80€ 195.05€
Viagra Generic25mg270 + 8 Pills184.26€ 175.49€
Kamagra100mg84 + 6 Pills264.44€ 251.85€
Viagra Generic150mg120 + 8 Pills177.58€ 169.12€
Viagra Generic200mg180 + 10 Pills277.56€ 264.34€

Men using sildenafil for erectile dysfunction should take a sildenafil dose only as needed one hour before anticipated sexual activity.

Contraindications for Revatio

You can take this ED medication with or without food. However, high-fat meals can impact the absorption of sildenafil, leading to lower peak plasma levels of the medication, which can translate to lower efficacy. Grapefruit juice can also interfere with how the body processes sildenafil, leading to more side effects. So, if you’re a half-grapefruit in the a.m. kind of guy, mention that to your healthcare provider before filling a sildenafil prescription.

Drugs Affecting or Metabolized by Hepatic Microsomal Enzymes

Keep sildenafil out of the reach of children and pets, and store the medication at room temperature between 68°F to 77°F (20°C to 25°C). You should always follow your doctor’s instructions regarding sildenafil dosing, but your total daily dosage should never exceed 100 milligrams. Even if you’re not getting results from a 100-milligram dose of sildenafil, don’t try to take more. If sildenafil isn’t helping with your lackluster erections, there are a few possible reasons. Another kind of treatment altogether (like therapy for psychological ED) Another kind of treatment altogether (like therapy for psychological ED) Addressing underlying health conditions that can contribute to ED Addressing underlying health conditions that can contribute to ED Additionally, taking sildenafil too early (we’re talking more than a few hours before having sex) won’t produce the effects you’re looking for. Do not take another dose for 24 hours.

How should this medicine be used?

It might be dangerous to use sildenafil if you have certain medical conditions or take specific drugs. If your healthcare provider told you not to engage in sexual activity because of a heart condition (like a history of heart attack; heart disease; heart failure; angina; or arrhythmia, also known as an irregular heartbeat), it’s probably best to abstain from having sex and taking sildenafil. Using sildenafil when you take medicines for high blood pressure or pulmonary arterial hypertension could cause a dangerous, potentially life-threatening dip in blood pressure. Avoid taking sildenafil with nitrates (medications for chest pain) such as isosorbide dinitrate, isosorbide mononitrate, nitroglycerin, and alpha-blockers or other blood pressure medications like riociguat. If you have a condition that puts you at higher risk of priapism—like sickle cell anemia, leukemia, Peyronie’s disease, or multiple myeloma—you should avoid sildenafil.

Azole Antifungals

There isn’t enough data to say whether sildenafil is safe for people with this eye condition. Sildenafil can interact with the nitrites found in certain recreational drugs popularly known as “poppers,” causing a dangerous drop in blood pressure. Don’t mix sildenafil with other ED drugs, like Cialis®, Levitra®, Revatio® (another brand name for sildenafil) or Stendra®. This can put you at risk for low blood pressure. More of something isn’t always better! People with pulmonary hypertension will take lower doses three times daily for the full duration of treatment.

  • Sildenafil 60mg may interact with blood pressure medications.
  • Use with caution if you have a history of priapism.
  • Blood tests may be required before starting treatment.
  • Regular medical check-ups are recommended.

Sildenafil is a generic prescription drug that widens arteries.

Clinical Pharmacology for Revatio

Aside from heart medications and other PDE5 inhibitors, taking sildenafil with ritonavir, ketoconazole, itraconazole, or clarithromycin (an antibiotic) can increase the concentration of sildenafil in your body and make you more likely to experience side effects. Talk with a healthcare professional before mixing sildenafil with over-the-counter supplements, which aren’t regulated in the same way as prescription drugs. Learn more about health and drug interactions in our sildenafil interactions guide. If you’re living with ED symptoms, you’re not alone. Sildenafil can make it easier to get and keep an erection so you can enjoy a fulfilling sex life.

Therapies for Erectile Dysfunction

Here’s what to remember when taking sildenafil for ED: Take it at least 30 to 60 minutes and no more than four hours before sexual stimulation. Also, avoid high-fat foods or meals that can slow absorption. Take it at least 30 to 60 minutes and no more than four hours before sexual stimulation. Don’t mix sildenafil with medications that can cause dangerous interactions. Unsure whether your meds are safe to combine with sildenafil? People know it far better as brand-name Viagra, a treatment for erectile dysfunction.

Side Effect Severity Frequency Notes
Headache Mild to moderate Common Usually subsides within hours
Flushing Mild Frequent Redness of face or neck
Nasal Congestion Mild Common Stuffiness in nasal passages

This is what it’s popularly known for.

Is Sildenafil Safe?

Regular exercise, a balanced diet, and quality sleep can maximize your overall health and sexual well-being. Consider alternative treatments if sildenafil doesn’t work for you. Other oral erectile dysfunction medications include tadalafil (generic for Cialis), avanafil (Stendra), vardenafil, and chewable Hard Mints. Your healthcare provider might also recommend adjusting your sildenafil dosage. Ready to find an erectile dysfunction treatment that works for you?

Dosage adjustments

Get advice from one of our healthcare providers to learn more about your options. Don’t be tempted to use expired medicines. Gianmarco Troiano & Giacomo Lazzeri (2021) The potential toxic combination of grapefruit juice and sildenafil, Toxin Reviews, 40:3, 334-337. Sildenafil citrate induced retinal toxicity-electroretinogram, optical coherence tomography, and adaptive optics findings. Do food and dose timing affect the efficacy of sildenafil? However, sildenafil is also used to treat high blood pressure in the lung’s arteries, a condition called pulmonary hypertension.

  • Take sildenafil on an empty stomach for faster effect.
  • It typically takes about 30-60 minutes to work.
  • Its effects can last for up to 4-6 hours.
  • Proper hydration can enhance its effectiveness.

For erectile dysfunction, men should only take doses as needed before sexual activity.

  • Keep track of any side effects to report promptly.
  • Avoid taking it with fatty foods for quicker absorption.
  • Use as part of a comprehensive approach to ED.
  • Medication adherence is key to effectiveness.

For pulmonary hypertension, doses are taken three times daily for as long as necessary. Sildenafil tablets are the most commonly used.

Medication Mechanism Common Uses Notes
Tadalafil PDE5 inhibitor Erectile dysfunction, BPH Longer duration, up to 36 hours
Vardenafil PDE5 inhibitor Erectile dysfunction Similar to sildenafil
Avanafil PDE5 inhibitor Erectile dysfunction Faster onset

Low-dose tablets (20 mg) are for pulmonary hypertension. Higher-dose tablets are appropriate for erectile dysfunction.

In case of emergency/overdose

That means you have to do a bit of sex planning when taking sildenafil. But you might be surprised at how sexy the anticipation can be—for you and your partner. Spend that time exploring new foreplay ideas or sharing your sexual fantasies. Avoid taking sildenafil if it’s expired. According to the FDA, you should skip taking any expired meds and safely dispose of them for the following reasons: Their chemical composition could be altered, making them unsafe to consume.

Long-term use

Their chemical composition could be altered, making them unsafe to consume. How can you tell if your medications are expired? Check the label for a date, likely next to the abbreviation “Exp.” Want more tips on how to get the most out of sildenafil? Read our guide on how to use Viagra for best results. It doesn’t really matter if you forget to take sildenafil because it’s designed for you to take it as you need it. Patients with pulmonary hypertension can also take a liquid sildenafil or be given an intravenous injection.

Medication Category Effect Examples
CYP3A4 inhibitors Increased sildenafil levels Ketoconazole, ritonavir
Antihypertensives Potential blood pressure drop Beta-blockers, diuretics
Nitrates Risk of hypotension Isosorbide dinitrate, nitroglycerin

Tablets: 20 mg (pulmonary hypertension), 25 mg, 50 mg, 100 mg Tablets: 20 mg (pulmonary hypertension), 25 mg, 50 mg, 100 mg Oral suspension: 10 mg/mL (pulmonary hypertension) Oral suspension: 10 mg/mL (pulmonary hypertension) Injection: 10 mg/12.5 mL (pulmonary hypertension) Injection: 10 mg/12.5 mL (pulmonary hypertension) Sildenafil is FDA-approved for erectile dysfunction and pulmonary hypertension.

Usual Geriatric Dose for Erectile Dysfunction

But be careful about accidentally doubling up on doses. Missing a dose before sex is no big deal, though doing so may impact the quality of your erection. However, forgetting you already took sildenafil and taking a subsequent dose within 24 hours can lead to complications, particularly if you go over 100 milligrams total. You should be aware of the potential side effects when taking any new drug. The most common side effects of sildenafil include: Most of these mild side effects will go away on their own as your body adapts to taking sildenafil.

Is Viagra prescribed in dosages of 100 mg, 150 mg, or 200 mg?

But sildenafil also comes with some more rare but potentially serious side effects like: Sudden loss of vision (potentially a sign of non-arteritic anterior ischemic optic neuropathy or NAION) Sudden loss of vision (potentially a sign of non-arteritic anterior ischemic optic neuropathy or NAION) Priapism (a painful erection lasting longer than four hours) Priapism (a painful erection lasting longer than four hours) If you experience any of these symptoms after taking sildenafil, seek immediate medical attention. And FYI: Even mild side effects can impact your life. If you get an upset stomach every time you take sildenafil, talk with a healthcare professional. They may recommend changing your dose or switching medications altogether. Read more about potential sildenafil reactions in our sildenafil side sildenafil citrate drug effects guide.