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The inside of the corpora cavernosa is like a sponge, with potential spaces that can fill with blood and distend (known as sinusoids). A layer of tissue that is like Saran Wrap, called the tunica albuginea, surrounds the corpora. Veins located just under the tunica albuginea drain blood out of the penis. Erections are neurovascular events, meaning that nerves and blood vessels (arteries and veins) are involved in the process of an erection and all must work properly to develop a hard erection that lasts long enough. Sexual stimulation can be tactile (for example by a partner touching the penis or by masturbation) or mental (for example by having sexual fantasies or viewing porn).

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Sexual stimulation or sexual arousal causes the nerves going to the penis to release a chemical, nitric oxide. Nitric oxide increases the production of another chemical, cyclic GMP (cGMP), in the muscle of the corpora cavernosa. The cGMP causes the muscles of the corpora cavernosa to relax, and this allows more blood to flow into the penis. The incoming blood fills the corpora cavernosa, making the penis expand. As blood flows into the penis, the pills to increase sex drive male corpora cavernosa swell and this swelling compresses the veins (blood vessels that drain the blood out of the penis) against the tunica albuginea. narcotic and alcohol abuse contribute to erectile dysfunction.

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Erectile dysfunction (ED), also known as impotence, is the inability to achieve or sustain a hard enough erection for satisfactory completion of sexual activity. Erectile dysfunction is different from other health conditions that interfere with male sexual function, such as: The penis contains three cylinders, the two corpora cavernosa, which are on the top of the penis (see Figure 1 below). These two cylinders are involved in erections. The third cylinder contains the urethra, the tube that the urine and ejaculate pass through, which runs along the underside of the penis. Spongy tissue that has muscles, fibrous tissues, veins, and arteries within it makes up the corpora cavernosa. testicles and lower testosterone levels. Low testosterone levels: Testosterone (the primary sex

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Hardening of the arteries to the penis and pelvic organs, atherosclerosis, causes insufficient blood flow into the penis. There is a close correlation between the severity of atherosclerosis in the coronary arteries and erectile dysfunction. For example, men with more severe coronary artery atherosclerosis (hardening of the arteries in the heart) also tend to have more erectile dysfunction than men with mild or no coronary artery atherosclerosis. Some doctors suggest that men with new onset erectile dysfunction undergo evaluation for silent coronary artery diseases (advanced coronary artery atherosclerosis that has not yet caused angina or heart attacks). Metabolic syndrome is associated with multiple risk factors for erectile dysfunction including: Cigarette smoking: Cigarette smoking aggravates atherosclerosis and can cause vasospasm (spasms of the arteries) thereby increasing the risk for erectile dysfunction. hormone in men) is not only necessary for

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Nerve or spinal cord damage: Damage to the spinal cord and nerves in the pelvis can cause erectile dysfunction. Nerve damage can be due to disease, trauma, or surgical procedures. Examples include: Injury to the spinal cord from automobile accidentsInjury to the pelvic nerves from prostate surgery for cancer (prostatectomy)Some surgeries for colorectal cancerRadiation to the prostateSurgery for benign prostatic enlargementMultiple sclerosis (a neurological disease with the potential to cause widespread damage to nerves)Long-term diabetes mellitus Examples include: Injury to the spinal cord from automobile accidentsInjury to the pelvic nerves from prostate surgery for cancer (prostatectomy)Some surgeries for colorectal cancerRadiation to the prostateSurgery for benign prostatic enlargementMultiple sclerosis (a neurological disease with the potential to cause widespread damage to nerves)Long-term diabetes mellitus Injury to the spinal cord from automobile accidents Injury to the pelvic nerves from prostate surgery for cancer (prostatectomy) Multiple sclerosis (a neurological disease with the potential to cause widespread damage to nerves) BPH: Benign enlargement of the prostate is associated with erectile dysfunction. Trauma: Trauma to the pelvis, including pelvic fracture, may cause erectile dysfunction, and an untreated penile fracture may result in erectile dysfunction. Substance abuse: Marijuana, heroin, cocaine, methamphetamine, crystal meth, and narcotic and alcohol abuse contribute to erectile dysfunction.Alcoholism, in addition to causing nerve damage, can lead to atrophy (shrinking) of the testicles and lower testosterone levels. sex drive (libido) but also is necessary

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Atherosclerosis can affect the arteries in the penis, as well as the arteries in the pelvis that supply the penile arteries. Diabetes mellitus also causes erectile dysfunction by damaging nerves that go to the penis, much like the effect of diabetes on nerves in other areas of the body (diabetic neuropathy).Diabetes can also affect the muscles in the penis, leading to trouble with erections.Smoking cigarettes, obesity, poor control of blood glucose levels, and having diabetes mellitus for a long time further increase the risk of erectile dysfunction in people with diabetes. Diabetes mellitus also causes erectile dysfunction by damaging nerves that go to the penis, much like the effect of diabetes on nerves in other areas of the body (diabetic neuropathy). Diabetes can also affect the muscles in the penis, leading to trouble with erections. Smoking cigarettes, obesity, poor control of blood glucose levels, and having diabetes mellitus for a long time further increase the risk of erectile dysfunction in people with diabetes.

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Hypertension (high blood pressure): Men with high blood pressure have an increased risk of developing erectile dysfunction. Cardiovascular diseases: The most common cause of cardiovascular diseases in the United States is atherosclerosis, the narrowing, and hardening of arteries that reduces blood flow. Atherosclerosis (a type of vascular disease) typically affects arteries throughout the body; hypertension, high blood cholesterol levels, cigarette smoking, and diabetes mellitus aggravate atherosclerosis.Hardening of the arteries to the penis and pelvic organs, atherosclerosis, causes insufficient blood flow into the penis.There is a close correlation between the severity of atherosclerosis in the coronary arteries and erectile dysfunction. For example, men with more severe coronary artery atherosclerosis (hardening of the arteries in the heart) also tend to have more erectile fildena 120 dysfunction than men with mild or no coronary artery atherosclerosis.Some doctors suggest that men with new onset erectile dysfunction undergo evaluation for silent coronary artery diseases (advanced coronary artery atherosclerosis that has not yet caused angina or heart attacks). Atherosclerosis (a type of vascular disease) typically affects arteries throughout the body; hypertension, high blood cholesterol levels, cigarette smoking, and diabetes mellitus aggravate atherosclerosis. Therefore, men with hypogonadism

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Compression of the veins prevents blood from leaving the penis. When the amount of cGMP decreases by the action of a chemical called phosphodiesterase type 5 (PDE5), the muscles in the penis tighten, and the blood flows into the penis decreases. With less blood coming into the penis, the veins are not compressed, allowing blood to drain out of the penis, and the erection goes down. The ability to achieve and sustain erections requires the following: A healthy nervous system that conducts nerve impulses in the brain, spinal column, and penis Healthy arteries in and near the corpora cavernosa that when stimulated can bring increased blood flow into the penis Healthy muscles and fibrous tissues within the corpora cavernosa can distend to allow the penis to fill with blood Adequate levels of nitric oxide in the penis Normal-functioning tunica albuginea that allows for compression of the veins Erectile dysfunction can occur if a man doesn't meet one or more of these requirements. The following are common causes of erectile dysfunction (many men have more than one potential cause): Aging: There are two reasons why older men are more likely to experience erectile dysfunction than younger men.

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First, older men are more likely to develop diseases (such as heart attacks, angina, cardiovascular disease, strokes, diabetes mellitus, and high blood pressure) that are associated with erectile dysfunction.Second, the aging process alone can cause erectile dysfunction in some men by causing changes in the muscle and tissue within the penis. First, older men are more likely to develop diseases (such as heart attacks, angina, cardiovascular disease, strokes, diabetes mellitus, and high blood pressure) that are associated with erectile dysfunction. Second, the aging process alone can cause erectile dysfunction in some men by causing changes in the muscle and tissue within the penis. Diabetes mellitus: Erectile dysfunction tends to develop 10 to 15 years earlier in diabetic men than among nondiabetic men. The increased risk of erectile dysfunction among men with diabetes mellitus may be due to the earlier onset and greater severity of atherosclerosis (hardening of the arteries) that narrows the arteries and thereby reduces the delivery of blood to the penis. (low testosterone with symptoms)

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